![]() ![]() ![]() Hirsch etal has demonstrated that patients with hematological malignancies are at a higher risk of respiratory tract infections and severe complications. Patients with hematological malignancies present a group of vulnerable patients. Secondary bacterial pneumonias, thrombotic complications, myocarditis, and gastrointestinal involvement are more prevalent in those with co morbidities such as hypertension, diabetes, cardiac disease, cancer and age > 70 years. The spectrum of COVID-19 varies from asymptomatic cases to acute respiratory distress syndrome (ARDS) and death. With the 2nd wave of COVID being reported in a lot of countries, better understanding of disease is very important. The 28-day survival was significantly better for patients in remission ( p = 0.04), non-severe infection (p = 0.00), and age < 60 years ( p = 0.05).Ĭorona virus disease 2019 (COVID-19) is caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus which originated in Wuhan, China. Importantly, death rate at 1 month was 50% and 60% in relapse/refractory and severe disease cohorts, respectively. One patient succumbed outside the study period on day 39. 14-day survival and 28-day survival for whole cohort was 85.4% and 80%, respectively. Overall, 20% ( n = 26) patients succumbed. Nearly three-fourth ( n = 95) of our patients were on anticancer treatment at time of infection, of which nearly two-third ( n = 59 64%) had a delay in chemotherapy. Median time to RT-PCR COVID-19 negativity was 17 days (7–49 days). Sixty seven patients (52%) needed oxygen For treatment of COVID-19 infection, half( n = 66) received antivirals. One-half patients (52%) had mild infection, while moderate and severe infections contributed to one-fourth each. ![]() Most of our patients had a lymphoid malignancy ( n = 91). Eleven percent patients were incidentally detected. Fever and cough were commonest presentation. ![]()
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